|Characteristics of prospective cohort studies evaluating sugar consumption and ovarian cancer risk|
|Reference||Location||Cases/cohort size (n)||Dietary assessment||Time frame of dietary assessment||Sugar variables||Covariates||Effect modifiers||Results|
|Kushi et al., 1999 ||Iowa (United States)||139/29,083||FFQ (126 items), 24-hour dietary recall among a subset||Current intake at baseline||“Breads, cereals, starches”, sweets||age, energy intake, # of live births, age at menopause, family history of ovarian cancer in a 1st-degree relative, hysterectomy/unilateral oophorectomy status, WHR, physical activity, pack-years smoked, educational||None||- association: breads, cereals, starches + association: sweets|
|Silvera et al., 2007 ||Canada||264/48776||FFQ (86 items)||Current intake at baseline||Total sugar||age, BMI, alcohol intake, HRT use, OC use, parity, age at menarche, menopausal status, energy intake, physical activity, fiber intake, study center, treatment allocation||Menopausal status, smoking history, age at menarche, HRT use, alcohol intake, parity||No association: total sugar +association: strong, suggested association with sugar among postmenopausal women No effect modification by smoking history, age at menarche, HRT use, alcohol intake, parity|
|Tasevska et al., 2012 ||8 states in USA (CA, FL, LA, NJ, NC, MI, GA, PA)||457/179,990||FFQ, DHQ (124 items)||1 year prior to index date||Total sugars, added sugar, sucrose, total fructose, added sucrose, added fructose||age, BMI, family history of cancer, marital status, smoking status and pack-years smoked, race, education, physical activity, energy intake, alcohol intake||HRT||- association: total sugars, added sugars, total fructose, sucrose, added sucrose, added fructose; no modification by HRT|
Abbreviations: FFQ- food frequency questionnaire, DHQ- diet history questionnaire, BMI- body mass index, HRT- hormone replacement therapy, ERT- unopposed estrogen replacement therapy, OC- oral contraceptives, WHR- waist-to-hip ratio, “+ association” - positive association, “- association”- negative association.
King et al.
King et al. BMC Cancer 2013 13:94 doi:10.1186/1471-2407-13-94