Table 2

Univariate survival analysis for Sirt1 expression and clinico-pathological parameters in PDAC
Cases Events Mean survival (months) Standard error Log-rank-test (p-value)
Age at diagnosis <=65 years 56 42 50.1 10.5 0.564
>65 years 57 47 25.1 4.4
WHO stage I 11 8 29.4 9.8 0.001
IIA 17 10 52.8 11.9
IIB 78 64 33.7 7.0
III 3 3 5.6 0.8
IV 4 4 11.9 4.1
Tumor stage T1 / / / /
T2 22 17 29.6 6.8 0.003
T3 88 69 39.6 7.3
T4 3 3 5.6 0.8
Nodal status N0 30 20 43.3 8.8 0.060
N1 83 69 32.2 6.6
State of metastasis M0 109 85 42.4 6.8 0.268
M1 4 4 11.9 4.1
Grade G1 7 6 16.8 2.5 0.058
G2 54 39 37.3 6.0
G3 52 44 29.7 7.9
SIRT1-expression low 81 58 54.1 8.9 0.002
high 32 31 13.0 1.7

Stenzinger et al.

Stenzinger et al. BMC Cancer 2013 13:450   doi:10.1186/1471-2407-13-450

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