Treatment with DOX high (0.2 mg/kg) causes toxicity and weight loss. Mice were weighed prior to each treatment. (A) Weights are plotted as the mean group weight (gram) at each treatment time point. Differences in the slope of average weights over time in the DOX high (0.2 mg/kg) treatment group were significantly lower (*) (p ≤ 0.05) in comparison to all other treatment groups. No significant differences in weight were found between all other treatment groups. (B) SEM ranges for each treatment group over time are provided.
Macura et al. BMC Cancer 2013 13:400 doi:10.1186/1471-2407-13-400