Table 1

SHAPE-2 study inclusion and exclusion criteria
Inclusion criteria Exclusion criteria
Female Presently using sex hormones
50-69 years of age Use of beta-blockers or oral corticosteroids
Postmenopausal (last menses >12 months) Smoking
Body mass index (BMI) 25–35 m/kg2 Alcohol or drug abuse
Sedentary lifestyle (<2 hours/week of at least moderately intensive activities (≥4 MET)) Diagnosed with breast cancer (present or history)
Willing to be randomly assigned to one of the three study arms Diagnosed with other cancer (present or <5 years of history), except fornon-melanoma skin cancer
Informed consent for all screening and study activities Diabetes mellitus or other (unstable) endocrine related diseases
Any disorder that might impede participation in the exercise programme
Following, or intention to follow, a structured weight loss programme elsewhere
Investigators opinion (successful fulfilling of the programme is highly unlikely)

van Gemert et al.

van Gemert et al. BMC Cancer 2013 13:395   doi:10.1186/1471-2407-13-395

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