Table 2

Association between consumers of alcoholic beverages and ovarian carcinoma, OCAC studies
Intake/d Ca/Co OR (95% CI)
Total alcohol 5,342/10,358
 None 2,269/4,296 1.0 (Ref)
 Up to 1 drink * 2,074/3,928 0.94 (0.85-1.03)
 1-2 drinks 560/1,112 0.97 (0.85-1.11)
 2-3 drinks 192/400 0.91 (0.74-1.11)
 >3 drinks 247/622 0.92 (0.76-1.10)
P trend 0.27
Beer
 None 4,016/7,472 1.0 (Ref)
 Up to 12 oz 1,179/2,570 0.92 (0.83-1.02)
 >12 oz 147/315 1.09 (0.86-1.37)
P trend 0.43
Wine
 None 2,821/5,307 1.0 (Ref)
 Up to 4 oz 2,057/3,984 0.94 (0.85-1.04)
 4-8 oz 261/522 1.00 (0.83-1.20)
 >8 oz 203/545 0.83 (0.68-1.01)
P trend 0.08
White wine
 None 2,110/4,114 1.0 (Ref)
 Up to 4 oz 1,053/2,032 0.93 (0.82-1.06)
 >4 oz 162/406 0.97 (0.77-1.21)
P trend 0.26
Red wine
 None 2,330/4,548 1.0 (Ref)
 Up to 4 oz 866/1,665 0.92 (0.81-1.05)
 >4 oz 129/336 0.90 (0.71-1.15)
P trend 0.11
Liquor
 None 3,599/6,865 1.0 (Ref)
 Up to 1 oz 1,535/3,061 0.97 (0.88-1.08)
 >1 oz 208/431 1.03 (0.85-1.26)
 P trend 0.82

Adjusted for age (<40; 40-49; 50-59; 60-69; 70+ years), smoking status (never, former, current), site (AUS, CON, DOV, GER, HAW, HOP, MAL, NCO, NEC, NJO, POL, SON), race/ethnicity (white nonHispanic; white Hispanic; black non Hispanic; Asian; other or unknown); menopausal status (pre/peri-menopausal; postmenopausal, unknown or missing), oral contraceptive use (<6mo, 6-22 mo, 23+ mo, unknown or missing), tubal ligation (yes; no; unknown or missing), endometriosis (yes; no; unknown or missing), hysterectomy (yes; no; unknown or missing), family history of breast or ovarian cancer in first-degree relatives (no; yes; unknown; no daughters or sisters), parity/age at last birth (nulliparous; 1-2 births/age ≤25 yrs at last pregnancy; 3+ births/age ≤25 yrs at last pregnancy; 1-2 births/age >25 years at last pregnancy; 3+ births/age >25 years at last pregnancy; yes if ever pregnant but unknown or missing age at last pregnancy age; no or unknown if ever pregnant and missing age at last pregnancy, interview year (1990-1994; 1995-1999; 2000-2004; 2005-2009; missing), age at menarche (8-10 yrs; 11 yrs; 12 yrs; 13 yrs; 14-21 yrs; <8 or ≥ 22 yrs), body mass index (continuous) and education (less than high school, high school, some college, completed college or university, completed graduate or professional degree, missing). Models include interaction terms between site and each covariate except alcohol.

* 1 drink = 10 grams ethanol.

† Models are also simultaneously adjusted for consumption of beer, wine and liquor intake.

‡ White/red wine information available from AUS, CON, DOV, HAW, HOP and NEC only. Models are simultaneously adjusted for beer and liquor intake.

Kelemen et al.

Kelemen et al. BMC Cancer 2013 13:28   doi:10.1186/1471-2407-13-28

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