Table 4

Risk of glioma associated with genotypes by smoking status
Genotype Smoking Cases, n(%) Controls, n(%) OR (95% CI)a Pinteractionb
LIG4: rs1805388
CC No 107 (27.9) 122 (31.8) 1.00 0.013/0.046
CT/TT No 121 (31.5) 96 (25.0) 1.39 (0.96-2.01)
CC Yes 56 (14.6) 100 (26.0) 0.62 (0.41-0.94)
CT/TT Yes 100 (26.0) 66 (17.2) 1.67 (1.11-2.50)
XRCC4: rs1805377
AA No 120 (31.2) 117 (30.5) 1.00 0.536/0.886
AG/GG No 108 (28.1) 101 (26.3) 0.99 (0.68-1.44)
AA Yes 59 (15.4) 78 (20.3) 0.70 (0.46-1.07)
AG/GG Yes 97 (25.3) 88 (22.9) 1.02 (0.69-1.50)

aAdjusted for age, gender and drinking status.

bP for additive interaction/P for multiplicative interaction.

Zhao et al.

Zhao et al. BMC Cancer 2013 13:234   doi:10.1186/1471-2407-13-234

Open Data