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Open Access Research article

Mammogram image quality as a potential contributor to disparities in breast cancer stage at diagnosis: an observational study

Garth H Rauscher1*, Emily F Conant2, Jenna A Khan1 and Michael L Berbaum3

Author Affiliations

1 School of Public Health, Division of Epidemiology and Biostatistics, University of Illinois at Chicago, M/C 923, Chicago, IL 60612, USA

2 Department of Radiology/Breast Imaging, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA

3 Institute for Health Research and Policy University of Illinois at Chicago, M/C 275, 1747 West Roosevelt Road, Chicago, IL 60608, USA

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BMC Cancer 2013, 13:208  doi:10.1186/1471-2407-13-208

Published: 26 April 2013

Abstract

Background

In an ongoing study of racial/ethnic disparities in breast cancer stage at diagnosis, we consented patients to allow us to review their mammogram images, in order to examine the potential role of mammogram image quality on this disparity.

Methods

In a population-based study of urban breast cancer patients, a single breast imaging specialist (EC) performed a blinded review of the index mammogram that prompted diagnostic follow-up, as well as recent prior mammograms performed approximately one or two years prior to the index mammogram. Seven indicators of image quality were assessed on a five-point Likert scale, where 4 and 5 represented good and excellent quality. These included 3 technologist-associated image quality (TAIQ) indicators (positioning, compression, sharpness), and 4 machine associated image quality (MAIQ) indicators (contrast, exposure, noise and artifacts). Results are based on 494 images examined for 268 patients, including 225 prior images.

Results

Whereas MAIQ was generally high, TAIQ was more variable. In multivariable models of sociodemographic predictors of TAIQ, less income was associated with lower TAIQ (p < 0.05). Among prior mammograms, lower TAIQ was subsequently associated with later stage at diagnosis, even after adjusting for multiple patient and practice factors (OR = 0.80, 95% CI: 0.65, 0.99).

Conclusions

Considerable gains could be made in terms of increasing image quality through better positioning, compression and sharpness, gains that could impact subsequent stage at diagnosis.

Keywords:
Breast cancer; Disparities; Screening; Mammography; Socioeconomic status