Table 5

Coefficients of all diagnostic models using either only expression values, protein abundance values, or both types of values in combination (65 controls vs. 224 EOC samples)
Genes/Proteins Coefficients (L1 and L2 penalized regression)
L1 7 Genes L2 13 Genes L1 4 Proteins L2 6 Proteins L1 5 Genes 5 Proteins L2 13 Genes 6 Proteins
105743 0.02 0.63 0.26
109227 0.05 −0.01
110071 0.17 0.26 0.16
228089 0.91 0.99 0.63 0.70
713562 0.34 0.34 0.22 0.29
115368 −0.18 0.36
119290 0.28 0.34
142487 0.15 0.12
157342 0.36 0.64 0.35 0.55
161567 −0.56 −0.27
162222 −1.34 −1.34 −1.58 −1.30
182018 −0.38 −0.09
205406 −0.83 −1.05 −0.54 −0.87
log2 MIF 0.09 −0.05 −0.24
log2 prolactin 0.67 0.62 0.47 0.53
log2 CA125 0.71 0.67 0.33 0.39
log2 leptin −0.32 −0.35 −0.55 −0.59
log2 osteopondin 0.05 −0.02
log2 IGF2 −0.31 −0.35 −0.47 −0.51
Intercept 3.93 4.90 −2.71 −2.77 4.91 7.31

Pils et al.

Pils et al. BMC Cancer 2013 13:178   doi:10.1186/1471-2407-13-178

Open Data