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Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer

Patrick C O´Leary1, Sarah A Penny1, Roisin T Dolan16, Catherine M Kelly1, Stephen F Madden3, Elton Rexhepaj1, Donal J Brennan1, Amanda H McCann12, Fredrik Pontén4, Mathias Uhlén5, Radoslaw Zagozdzon1, Michael J Duffy27, Malcolm R Kell6, Karin Jirström8 and William M Gallagher1*

Author Affiliations

1 UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin 4, Ireland

2 UCD School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland

3 Molecular Therapeutics for Cancer Ireland, National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin, Ireland

4 Department of Pathology, University Hospital of Uppsala, Uppsala, Sweden

5 Royal Institute of Technology, Stockholm, Sweden

6 Department of Breast & Endocrine Surgery, Mater Misericordiae University Hospital, Dublin 7, Ireland

7 UCD Clinical Research Centre, St. Vincent’s University Hospital, Dublin 4, Ireland

8 Division of Pathology, Department of Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden

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BMC Cancer 2013, 13:175  doi:10.1186/1471-2407-13-175

Published: 2 April 2013

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