Table 1 |
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|
Enumeration and genomic profiling of circulating tumor cells (CTCs) from 20 castration resistant prostate cancer patients |
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|
Patient No. |
CTC/7.5 mL |
IE/FACS |
Days from draw to IE/FACS |
No. of cells collected as input for WGA |
aCGH |
|
|
|||||
|
1 |
1 |
n.d. |
N.A. |
N.A. |
N.A. |
|
2 |
1 |
n.d. |
N.A. |
N.A. |
N.A. |
|
3 |
85 |
Yes |
1 |
50 |
Yes |
|
4 |
12 |
Insufficient sample |
N.A. |
N.A. |
N.A. |
|
5 |
144 |
Failed due to machine error |
1 |
N.A. |
N.A. |
|
6 |
6 |
Insufficient sample |
N.A. |
N.A. |
N.A. |
|
7 |
10 |
Insufficient sample |
N.A. |
N.A. |
N.A. |
|
8 |
2 |
n.d. |
N.A. |
N.A. |
N.A. |
|
9 |
590 |
Yes |
1 |
20 × 2 |
Yes (duplicate) |
|
10 |
151 |
Yes |
4 |
20 |
Yes |
|
11 |
9 |
Yes |
2 |
20 |
Yes |
|
12 |
2 |
n.d. |
N.A. |
N.A. |
N.A. |
|
13 |
55 |
Yes |
1 |
20 |
Yes |
|
14 |
590 |
Yes |
2 |
20 |
Yes |
|
15 |
42 |
Yes |
2 |
33 |
WGA failed |
|
16 |
0 |
n.d. |
N.A. |
N.A. |
N.A. |
|
17* |
54 |
Yes |
1 |
20 |
Yes |
|
18 |
33 |
Yes |
1 |
20 |
Yes |
|
19 |
34 |
Yes |
2 |
20 |
Hybridization failed |
|
20* |
12 |
Yes |
1 |
18 |
Yes |
|
|
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|
*Patients with available matched primary tumor IE/FACS-immunomagnetic enrichment and fluorescence activated cell sorting; aCGH-array comparative genomic hybridization; WGA-whole genome amplification; n.d.-not done; N.A.-not applicable |
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|
Magbanua et al. BMC Cancer 2012 12:78 doi:10.1186/1471-2407-12-78 |
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