Table 1 |
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|
Expression of BRMS1 according to number of positive cases, intensity and subcellular localization |
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|
1No. positive (%) |
Intensity (%) |
Score index (%) |
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|
|
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|
Nucleus |
Cytoplasm |
Nucleus |
Cytoplasm |
||||
|
|
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|
Total |
Nucleus |
Cytoplasm |
Strong2 |
Strong |
High3 |
High |
|
|
|
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|
Nevi |
15 (100) |
13 (87) |
13 (87) |
10 (67) |
7 (47) |
8 (53) |
1 (7) |
|
|
|||||||
|
Primary Melanomas |
136 (88) |
32 (20) |
134 (86) |
14 (9) |
90 (58) |
7 (5) |
77 (50) |
|
|
|||||||
|
SSM4 |
83 (89) |
17 (20) |
82 (88) |
7 (8) |
61 (66) |
2 (2) |
54 (58) |
|
|
|||||||
|
NM5 |
53 (85) |
15 (24) |
52 (84) |
7 (11) |
29 (45) |
5 (8) |
23 (37) |
|
|
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|
Metastases |
62 (90) |
33 (48) |
50 (72) |
17 (24) |
18 (26) |
15 (22) |
13 (19) |
|
|
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|
1Includes all positive cases 2Strong staining intensity includes moderate and strong intensity 3High score index defined as ≥ 4 4SSM; Superficial spreading melanoma 5NM; Nodular melanoma |
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|
Slipicevic et al. BMC Cancer 2012 12:73 doi:10.1186/1471-2407-12-73 |
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