Problems with current analysis methods. For crude samples, MSP may indicate that "a region was 50% methylated" while massARRAY indicates that "all CpG sites are 50% methylated". The methylation pattern may be A (extreme pattern) or B (variable pattern). ○, unmethylated CpG site; ●, methylated CpG site.
Yokoyama et al. BMC Cancer 2012 12:67 doi:10.1186/1471-2407-12-67