Figure 4.

PI3KC3-independent autopahgy induced by proteasome inhibitors in ovarian cancer cells. A, Ovarian cancer cells were treated with 5 μM of MG132 in the absence or presence of wortmannin (WT) or 3-MA, and AVs formation was analyzed using AO staining. B, Ovarian cancer cells were treated with 5 μM of MG132 in the absence or presence of WT or 3-MA, and LC3 transition was analyzed using Western blot analysis. C, OVCAR3 cells were treated with the indicated proteasome inhibitor in the absence or presence of WT or 3-MA, and AVs formation was measured using AO staining. D, OVCAR3 cells were treated with the indicated proteasome inhibitor (PI) in the absence or presence of WT or 3-MA, and LC3 transition was analyzed using Western blot analysis.

Liu et al. BMC Cancer 2012 12:622   doi:10.1186/1471-2407-12-622
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