Table 4 |
|||
| Joint effects of unfavorable genotypes in case patients and control subjects in Chinese | |||
| Risk group (no. unfavorable genotypes) | Cases | Controls | OR (95% CI)* |
| Reference groupa (n = 0) | 147 | 205 | Reference |
| Low-risk reference group (n = 1) | 96 | 83 | 1.51 (1.05- 2.17) |
| Medium-risk group (n = 2) | 108 | 76 | 1.86 (1.30-2.67) |
| High-risk group b (n ≥3) | 11 | 3 | 4.86 (1.33-17.71) |
| P for trend | <0.001 | ||
*Adjusted for age, gender, smoking status, and pack-years.
aReference group: GPX1 promoter: CC, MnSOD V16A: TT, SOD3 T58A: GG, and NOS1 3' UTR: CT+TT.
bBecause the subject number in group ‘4’ was sparse (one control and three patients), the subjects with greater than three unfavourable genotypes were combined as the high-risk group.
Zhao et al. BMC Cancer 2012 12:617 doi:10.1186/1471-2407-12-617
