Table 3

Multivariate survival analysis
All-cause mortality Cancer mortality Other-cause mortality
HR 95% CI P-Value HR 95% CI P-Value HR 95% CI P-Value
Lower Upper Lower Upper Lower Upper
Diabetes status
Previously diagnosed Reference
Previously undiagnosed 1.13 0.97 1.32 0.11 1.08 0.84 1.40 0.54 1.29 1.02 1.63 0.03
Age at cancer diagnosis (years)
66-70 Reference
71-75 1.12 0.88 1.44 0.35 1.31 0.89 1.92 0.18 0.87 0.57 1.31 0.50
76-80 1.47 1.16 1.85 <0.01 1.37 0.93 2.02 0.11 1.40 0.96 2.02 0.08
>80 1.90 1.53 2.36 <0.0001 1.46 1.02 2.09 0.04 2.16 1.54 3.03 <0.0001
Race/ethnicity
White Reference
Black 1.08 0.83 1.40 0.58 1.07 0.69 1.66 0.75 0.95 0.61 1.47 0.82
Hispanic 0.86 0.61 1.21 0.37 1.02 0.61 1.72 0.93 1.15 0.69 1.89 0.60
Other 0.92 0.56 1.51 0.74 0.77 0.28 2.08 0.60 1.07 0.53 2.17 0.86
Year of diagnosis
2001 Reference
2002 1.06 0.89 1.27 0.50 1.23 0.89 1.70 0.22 1.20 0.91 1.57 0.19
2003 1.07 0.89 1.29 0.50 1.05 0.75 1.47 0.79 1.09 0.81 1.45 0.58
2004 0.90 0.73 1.10 0.29 1.05 0.73 1.50 0.80 0.90 0.66 1.24 0.53
2005 1.02 0.83 1.25 0.86 1.15 0.81 1.63 0.44 0.95 0.68 1.33 0.75
Estrogen (ER) and progesterone (PR) receptor status
ER or PR positive Reference
ER and PR positive 0.84 0.70 1.01 0.07 0.64 0.47 0.88 0.01 0.98 0.73 1.31 0.89
ER and PR negative 1.31 1.04 1.64 0.02 1.56 1.10 2.21 0.01 0.90 0.61 1.34 0.61
Unknown/missing 0.86 0.70 1.05 0.14 0.58 0.40 0.83 <0.01 1.06 0.77 1.45 0.74
Histologic grade
1 Reference
2 1.14 0.94 1.39 0.18 2.24 1.42 3.53 <0.01 0.86 0.66 1.12 0.27
3 1.54 1.26 1.88 <0.0001 3.17 2.01 5.01 <0.0001 1.20 0.90 1.59 0.21
4 1.15 0.76 1.72 0.51 3.32 1.65 6.68 <0.01 0.75 0.39 1.46 0.40
Unknown/missing 1.66 1.32 2.08 <0.0001 4.04 2.48 6.57 <0.0001 0.91 0.64 1.28 0.58
NCI Comorbidity Index
0 Reference
1 1.37 1.17 1.61 <0.01 0.99 0.76 1.30 0.96 1.64 1.27 2.12 <0.01
≥ 2 1.83 1.55 2.16 <0.0001 1.11 0.82 1.49 0.51 2.53 1.95 3.27 <0.0001
Indicators of poor performance
0 Reference
≥ 1 1.27 1.10 1.46 <0.01 1.00 0.78 1.28 0.97 1.66 1.33 2.08 <0.0001
Types of physician visits
None Reference
Primary care and medical specialist 0.56 0.44 0.72 <0.0001 0.44 0.30 0.65 <0.0001 0.61 0.40 0.93 0.02
Primary care, no medical specialist 0.70 0.54 0.92 0.01 0.65 0.43 0.98 0.04 0.63 0.39 1.00 0.05
Medical specialist, no primary care 0.72 0.54 0.96 0.02 0.43 0.26 0.70 <0.01 1.11 0.70 1.75 0.66
Other specialist only 1.02 0.69 1.50 0.94 0.76 0.39 1.46 0.40 1.04 0.55 1.97 0.91
Preventive services
0 Reference
1 0.78 0.63 0.96 0.02 0.78 0.55 1.10 0.15 0.99 0.69 1.42 0.95
≥ 2 0.53 0.43 0.64 <0.0001 0.41 0.29 0.57 <0.0001 0.73 0.52 1.02 0.07
Percent in census tract with some college
<25% Reference
≥25% 1.09 0.96 1.24 0.20 1.16 0.92 1.46 0.21 1.24 1.01 1.52 0.04
Percent in census tract living in poverty
<5% Reference
5-7% 0.97 0.80 1.19 0.79 0.94 0.67 1.31 0.72 0.97 0.72 1.30 0.82
8-12% 0.94 0.79 1.12 0.48 0.80 0.59 1.10 0.17 0.92 0.71 1.20 0.55
>12% 1.07 0.90 1.27 0.45 0.93 0.69 1.25 0.61 0.93 0.71 1.22 0.62
Type of geographic area
Large metropolitan Reference
Metropolitan 0.99 0.86 1.15 0.90 0.80 0.62 1.03 0.09 0.92 0.73 1.15 0.47
Urban 0.97 0.75 1.25 0.80 0.63 0.38 1.06 0.08 0.77 0.49 1.22 0.26
Less urban/rural 0.84 0.67 1.04 0.11 0.60 0.39 0.90 0.01 1.09 0.79 1.51 0.58

HR: Hazard ratio. CI: Confidence interval.

Griffiths et al.

Griffiths et al. BMC Cancer 2012 12:613   doi:10.1186/1471-2407-12-613

Open Data