Table 4

Patient self -evaluation of nausea and vomiting during the 1stCT cycle (ITT population)
Placebo n = 217 Cocculine n = 214 All patients n = 431 p
Nausea frequency 0.59†
missing data 16 19 35
number of patients evaluable 201 195 396
Number of patients with at least 1 episode of nausea, n (%) 164 (81.6) 155 (79.5) 319 (80.6)
Nausea severity 0.61*
missing data 16 19 35
number of patients evalubale 201 195 396
Median (min-max) 0.56 (0–8.5) 0.58 (0–8.3) 0.56 (0–8.5)
Vomiting frequency 0.56†
missing data 31 19 50
number of patients evaluable 186 170 356
Number of patients with at least 1 episode of vomiting, n (%) 51 (27.4) 42 (24.7) 93 (26.1)
Vomiting severity
missing data 22 25 47 0.44*
number of patients evaluable 195 189 384
Median (min-max) 0.00 (0–7.60) 0.00 (0–5.0) 0.00 (0–7.60)

*: Mann–Whitney U test †: Person’s chi-square test.

Pérol et al.

Pérol et al. BMC Cancer 2012 12:603   doi:10.1186/1471-2407-12-603

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