Table 3

Odds ratios of AR expression by testosterone tertiles in natural postmenopausal women with ER-positive breast cancer
Testosterone tertiles, ng/ml
≤0.328 0.328-0.474 > 0.474 P trend
All ages
 AR expression
  Absent / poor-moderate 8/70 11/73 12/55
  age-adjusted OR (95% CI) 1 1.31 (0.50-3.46) 1.92 (0.73-5.02) 0.189
  High / poor-moderate 42/70 45/73 62/55
  age-adjusted OR (95% CI) 1 1.04 (0.61-1.77) 1.86 (1.10-3.16) 0.020
<65 years
 AR expression
  Absent / poor-moderate 3/27 6/39 5/25
  age-adjusted OR (95% CI) 1 1.38 (0.32-6.05) 2.03 (0.43-9.63) 0.374
  High / poor-moderate 18/27 23/39 21/25
  age-adjusted OR (95% CI) 1 0.88 (0.40-1.95) 1.26 (0.55-2.91) 0.582
≥65 years
 AR expression
  Absent / poor-moderate 5/43 5/34 7/30
  age-adjusted OR (95% CI) 1 1.25 (0.33-4.70) 2.00 (0.58-6.90) 0.282
  High / poor-moderate 24/43 22/34 41/30
  age-adjusted OR (95% CI) 1 1.13 (0.54-2.37) 2.42 (1.22-4.82) 0.011

NOTES. Androgen receptor (AR) expression: absent, 0%; poor, ≥1 to 30%; moderate, >30 to 60%, high: >60%. Estrogen receptor (ER) -positive: ER expression ≥10%.

Secreto et al.

Secreto et al. BMC Cancer 2012 12:599   doi:10.1186/1471-2407-12-599

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