Table 3

Cancer clinical trial understanding
Question items answers N %
Q#10 Which method do you think would be more effective in determining the effectiveness of the new drug? 1. Give the new drug to 1000 newly diagnosed cancer patients. 100 14.8
2. Give the new drug to 500 newly diagnosed cancer patients and give the currently used drug to 500 other newly diagnosed patients and see which group improves the most. 361 53.5
3. Not sure 214 31.7
Q#11 Randomization 1. Patients should be allowed to select the test group that they want. 214 31.7
2. Patients need to be assigned to a test group randomly to make the test accurate. 167 24.7
3. It doesn’t make any difference; either approach will work. 106 15.7
4. Not sure 188 27.9

Q#12 If a doctor were to tell you that patients in a clinical trial were to be assigned to the new therapy and the standard

therapy randomly, do you understand randomly to mean that patients would be assigned by:*

1. The severity of their disease. 235 33.0
2. An independent factor such as the two last digits of a patient’s telephone number.∗ 38 5.3
3. The kind of health insurance that they have. 14 2.0
4. The doctor depending on which group needs more participants. 311 43.7
5. I am not sure what “randomly” means. 114 16.0
Q#13 If a doctor were to tell you that patients in a clinical trial were to be assigned to the new therapy and the standard therapy randomly, do you understand standard therapy to mean:* 1. An average cancer therapy, not the best and not the worst. 106 15.0
2. The best available therapy for that particular cancer. 317 44.9
3. A placebo or sugar pill with no medical value. 5 0.7
4. An experimental therapy involving a new drug for cancer. 79 11.2
5. I am not sure what “standard therapy” means. 199 28.2

*Multiple selections were allowed.

Lee et al.

Lee et al. BMC Cancer 2012 12:594   doi:10.1186/1471-2407-12-594

Open Data