Table 1

Patient and treatment characteristics
Patient characteristics n % n %
Age at FD (yrs) Prior RT
Median 56 yes 43 44
Min 30 no 54 56
Max 74 Median dose (Gy) 50
Age at IORT (yrs) Distant metastasis prior to IORT
Median 60 History of resected metastasis 13 13
Min 31 Resection during present surgery 5 5
max 78 both 2 2
none 77 79
Time FD to IORT (mo)
Median 30 Type of present surgery
Min 5 AR 21 22
Max 181 APR 38 39
Pelvic exenteration/bone resection 32 33
Gender other 6 6
Male 59 61
Female 38 39 Resection Status (present surgery)
R0 36 37
No. of recurrence R1 32 33
First 83 86 R2 29 30
Multiple 14 14
EBRT in relation to present surgery
T stage at FD Neoadjuvant RT 6 6
T1 6 6 Neoadjuvant RCHT 40 41
T2 28 29 Adjuvant RT 0 0
T3 57 59 Adjuvant RCHT 8 8
T4 5 5 none 43 44
unknown 2 2
Adjuvant CHT
N stage at FD Yes 33 34
N0 54 56 No 64 66
N+ 41 42
unknown 2 2 IORT dose (Gy)
<10 1 1
M stage at FD 10 32 33
M0 92 95 12 18 19
M1 (all resected) 5 5 15 35 36
18 8 8
UICC stage at FD 20 3 3
I 28 29
II 25 26 IORT electron energy (MeV)
III 37 38 Median 8
IV 5 5 Min 6
Unknown 2 2 Max 18
Type of primary surgery IORT cone size (cm)
AR 65 67 Median 6.5
APR 27 28 Min 5
Local excision 5 5 Max 10

n: number of patients, %: percentage, FD: first diagnosis, yrs: years, Min: minimum, Max: maximum, IORT: intraoperative radiation therapy, mo: Months, No.: number, UICC: Union internationale contre le cancer, RT: radiotherapy, AR: anterior resection, APR: abdominoperineal resection, R0: complete resection without microscopic residual disease, R1: microscopic residual disease, R2: gross residual disease, EBRT: external beam radiation therapy, RCHT: radiochemotherapy, CHT: chemotherapy, Gy: Gray, MeV: mega electron volts, cm: centimeter.

Roeder et al.

Roeder et al. BMC Cancer 2012 12:592   doi:10.1186/1471-2407-12-592

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