Table 2

Estimated odds ratios for taking selective COX-2 Inhibitors during various prior duration
Duration prior to index date Colon cancer patients Controls Odds Ratio 95% confidence intervals p-value
# with at least 1 prescription # of nonusers # with at lease 1 prescription # of nonusers
all subjects aged 18-100 years old
5 years 2588 18872 9435 69896 0.51 (0.29, 0.90) 0.021
3 years 2393 25117 8293 90607 0.58 (0.39, 0.86) 0.007
1year 1264 31959 4153 121708 0.60 (0.46, 0.80) <.001
6 months 822 35401 2619 123242 0.72 (0.56, 0.93) 0.012
3 months 533 35690 1652 124209 0.80 (0.64, 1.01) 0.056
subjects with aged 65-100 years old
5 years 2243 10145 8242 37553 0.57 (0.31, 1.07) 0.079
3 years 2073 13600 7247 49098 0.63 (0.41, 0.97) 0.035
1year 1092 19000 3630 66182 0.64 (0.48, 0.88) 0.005
6 months 706 19386 2282 67530 0.72 (0.55, 0.95) 0.021
3 months 461 19631 1450 68362 0.83 (0.65, 1.07) 0.147
subjects with aged 18-64 years old
5 years 345 8727 1193 32344 0.36 (0.08, 1.67) 0.193
3 years 320 11517 1046 41508 0.45 (0.15, 1.34) 0.152
1year 172 15959 524 55525 0.53 (0.25, 1.11) 0.090
6 months 116 16015 336 55713 0.82 (0.46, 1.48) 0.520
3 months 72 16059 201 55848 0.73 (0.43, 1.26) 0.262
male subjects
5 years 1185 11697 4175 43446 0.48 (0.19, 1.24) 0.131
3 years 1085 15145 3673 54675 0.57 (0.30, 1.08) 0.085
1year 563 20298 1799 70685 0.59 (0.38, 1.91) 0.016
6 months 366 20495 1095 71389 0.70 (0.47, 1.05) 0.087
3 months 237 20624 660 71824 0.80 (0.56, 1.13) 0.203
female subjects
5 years 1403 7175 5260 26450 0.52 (0.25, 1.08) 0.080
3 years 1308 9972 4621 35931 0.59 (0.35, 0.98) 0.042
1year 701 14661 2354 51023 0.61 (0.42, 0.89) 0.009
6 months 456 14906 1523 51854 0.73 (0.52, 1.01) 0.056
3 months 296 15066 992 52385 0.80 (0.60, 1.07) 0.136

Yang et al.

Yang et al. BMC Cancer 2012 12:582   doi:10.1186/1471-2407-12-582

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