Table 2

Univariate analysis of disease-free and overall patient survivals with hepatocellular carcinoma

Clinicopathological Parameters

Median Disease-free survival

P value

Median Overall survival

P value


Age

< 65 years

237

0.349

1267

0.673

≥ 65 years

594

1234

Gender

Male

673

0.079

1283

0.568

Female

283

1092

Virus

HBV

237

0.178

1211

0.968

HCV

325

1283

None

847

1234

Miran Criteria

In

847

0.061

1940

0.006

Out

256

572

AFP

High (n = 20)

237

0.004

573

0.042

> 10 ng/mL

Low (n = 20)

847

1818

≤ 10 ng/mL

FGF19T

High (n = 20)

283

0.021

628

0.018

Low (n = 20)

413

1758

Tumor size

< 5 cm

717

0.171

1428

0.028

≥ 5 cm

256

498

Histologic type of tumor

Well differentiated

673

0.813

1428

0.712

Moderately differentiated

323

1234

Poorly differentiated

594

1092

Formation of fibrous capsule

Present

413

-------

1267

-------

Absent

64

64

Capsular infiltration

Present

403

0.853

1234

0.725

Absent

64

64

Septal formation

Present

325

0.872

1230

0.777

Absent

413

1283

Serosal invasion

Present

104

-------

172

-------

Absent

413

1267

Portal invasion

Present

283

825

0.105

Absent

881

1940

Hepatic vein invasion

Present

256

0.215

573

0.150

Absent

597

1428

Intrahepatic metastasis

Present

283

0.020

628

0.020

Absent

881

1983

Bile duct invasion

Present

403

-------

1267

-------

Absent

413

573

Lymph node metastasis

Present

256

-------

347

-------

Absent

413

1267

Pathological stage

II

1373

-------

2085

0.060

III

594

1234

IV

237

572


HBV hepatitis B virus, HCV hepatitis C virus, AFP alpha-fetoprotein

Miura et al. BMC Cancer 2012 12:56   doi:10.1186/1471-2407-12-56

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