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Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors

Luísa Pereira, Pedro Soares, Valdemar Máximo and David C Samuels*

BMC Cancer 2012, 12:53 doi:10.1186/1471-2407-12-53

Pre-publication versions of this article and reviewers' reports

Original Submission - Version 1 Manuscript 28 Sep 2011
Reviewer's Report Anita Kloss-Brandstaetter 05 Dec 2011
Reviewer's Report Kyle Furge 16 Dec 2011
Reviewer's Report Laura Greaves 02 Jan 2012
Resubmission - Version 2 Manuscript Author's comment 19 Jan 2012
Editorial acceptance 23 Jan 2012
Published 02 Feb 2012