Table 3

Subcellular localization of Ep-ICD and EpEx in metastatic and non-metastatic PTMC
Protein localization Metastatic (mean ± SD) Non-metastatic (mean ± SD) P-value AUC A.sig
EpEx cytoplasm 3.00 ± 1.67 1.91 ± 1.16 0.095 0.694 0.098
EpEx membrane 4.64 ± 1.08 5.64 ± 1.51 0.026 0.243 0.029
Loss of membranous EpEx 2.36 ± 1.08 1.36 ± 1.51 0.026 0.757 0.029
Ep-ICD nucleus 1.96 ± 0.86 1.22 ± 0.45 0.007 0.783 0.016
Ep-ICD cytoplasm 5.37 ± 0.33 4.72 ± 1.07 0.016 0.766 0.024
Ep-ICD membrane 1.30 ± 1.07 1.93 ± 1.61 0.348 0.391 0.351
ESLI (loss of membranous EpEx + Ep-ICDnuc + Ep-ICD cyto) 9.69 ± 2.01 7.30 ± 2.39 0.008 0.808 0.009

Kunavisarut et al.

Kunavisarut et al. BMC Cancer 2012 12:523   doi:10.1186/1471-2407-12-523

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