Table 4

Cellular functions of selected genes that are differentially expressed in GC specimens that overexpress Snail
Probe ID Gene acronym Gene name Accession No. P value
Cancer cell–ECM adhesion
ILMN_1759487 EGFLAM EGF-like, fibronectin type III, and laminin G domains (↑) NM_182801 0.005
ILMN_2114812 ONECUT1 One cut homeobox 1 (↓) NM_004498 0.002
ILMN_2374449 SPP1 Secreted phosphoprotein 1 (↑) NM_000582 0.004
ECM protein regulation
ILMN_1676452 ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 (↑) NM_080722 0.005
ILMN_1759487 EGFLAM EGF-like, fibronectin type III, and laminin G domains (↑) NM_182801 0.005
ILMN_1683453 FRAS1 Fraser syndrome 1 (↓) NM_020875 0.003
ILMN_1791057 IFNAR2 Interferon (alpha, beta, and omega) receptor 2 (↑) NM_207585 0.001
ILMN_1756455 IL5RA Interleukin 5 receptor, alpha (↓) NM_000564 0.004
ILMN_1747850 CRIM2 Kielin/chordin-like protein (↑) NM_199349 0.005
ILMN_1743301 MSR1 macrophage scavenger receptor 1 (↓) NM_002445 0.002
ILMN_2374449 SPP1 secreted phosphoprotein 1 (↑) NM_000582 0.004
ILMN_2256050 SERPINA1 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (↑) NM_000295 0.002
ILMN_2060115, ILMN_1759818 SORL1 Sortilin-related receptor, L(DLR class) A repeats-containing (↑) NM_003105 0.003 <0.001

NOTE: ↑, upregulation; ↓, downregulation.

Shin et al.

Shin et al. BMC Cancer 2012 12:521   doi:10.1186/1471-2407-12-521

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