Table 1 |
||||||
| Comparison of expression data for VEGF-B, VEGF-C and VEGF-D with previously published reports | ||||||
| VEGF family member | Own data | Published data | ||||
| Δ expression | Δ expression | Sampling method | Other confounders | Refs | ||
| Resection | Biopsy | |||||
| VEGF-B | = | ↗ *** | = | Resection | - | [5] |
| = | Resection | Rectal incl. | [7] | |||
| = | Resection | Rectal incl. | [8] | |||
| VEGF-C | ↗ * | ↗ *** | = | Resection | - | [5] |
| ↗ | n.s. | Rectal incl. | [6] | |||
| ↗ | Resection | Rectal incl. | [7] | |||
| = | Resection | Rectal incl. | [8] | |||
| = | Biopsy | Rectal incl. | [14] | |||
| VEGF-D | ↘ *** | = | ↘ | n.s. | Rectal incl. | [6] |
| ↘ | Resection | Rectal incl. | [7] | |||
| ↘ | Resection | Rectal incl. | [8] | |||
| ↘ | Biopsy | Rectal incl. | [14] | |||
Δ expression: differential expression in carcinoma samples compared to healthy tissue samples.
↗: significantly increased.
↘: significantly decreased.
=: no significance.
n.s.: not specified.
Rectal incl.: rectal samples included in the analysis.
*: p<0.05 with Wilcoxon signed rank test.
***: p<0.001 with Wilcoxon signed rank test.
Pringels et al. BMC Cancer 2012 12:515 doi:10.1186/1471-2407-12-515