Array analysis of the presence of HPV DNA in negative (A) and HPV-16 positive (B) controls derived from cervical cytobrush specimens. For each sample, a pair of primers amplify a fragment of human gene CFTR that is detected in the array as a positive genomic control (Controls of genomic DNA, in blue type), and another pair of primers amplify a modified plasmid that is included in the reaction mix as a control for PCR reaction (Controls of PCR reaction, in red type). Markers are used to align the array for the correct positioning and identification of HPV-specific probes, which are spotted into the array.
Galvan et al. BMC Cancer 2012 12:512 doi:10.1186/1471-2407-12-512