Table 3 |
|||
| Association of smoking with nasal malignancies | |||
| Controls (%) | Cases (%) | OR (95% CI) | |
| All study participants | |||
| Reference* | 986 (41.1) | 135 (31.6) | 1.00 |
| Smoking (ever) | 1415 (58.9) | 292 (68.4) | 1.60 (1.24–2.07) |
| Smoking (per pack-year) | 1415 (58.9) | 292 (68.4) | 1.06 (1.05–1.07) |
| Pack-years (quartiles) <8.6 | 352 (14.7) | 36 (8.4) | 0.53 (0.35–1.18) |
| 8.6 < 14.5 | 345 (14.4) | 32 (7.5) | 0.67 (0.42–1.06) |
| 14.5 < 21.75 | 365 (15.2) | 49 (11.5) | 1.05 (0.70–1.58) |
| 21.75+ | 354 (14.7) | 175 (41.0) | 4.11 (3.01–5.62) |
| Impact of quitting | |||
| Reference* | 986 (65.0) | 135 (70.6) | 1.00 |
| Duration since quitting (tertiles) <15 years | 158 (10.4) | 22 (11.5) | 1.11 (0.69–1.79) |
| 15–27 years | 175 (11.5) | 22 (11.5) | 1.13 (0.73–1.75) |
| 28+ years | 199 (13.1) | 12 (6.3) | 0.44 (0.26–0.74) |
* Non-smokers.
Adjustments: Year of birth, community size, educational attainment, nasal snuff package-years, years of exposure to hardwood dust, asbestos, organic solvents, use of nasal spray/nasal lavage and ever-use of insecticides in homes.
Greiser et al. BMC Cancer 2012 12:506 doi:10.1186/1471-2407-12-506
