Table 3

Association of smoking with nasal malignancies
Controls (%) Cases (%) OR (95% CI)
All study participants
Reference* 986 (41.1) 135 (31.6) 1.00
Smoking (ever) 1415 (58.9) 292 (68.4) 1.60 (1.24–2.07)
Smoking (per pack-year) 1415 (58.9) 292 (68.4) 1.06 (1.05–1.07)
Pack-years (quartiles) <8.6 352 (14.7) 36 (8.4) 0.53 (0.35–1.18)
8.6 < 14.5 345 (14.4) 32 (7.5) 0.67 (0.42–1.06)
14.5 < 21.75 365 (15.2) 49 (11.5) 1.05 (0.70–1.58)
21.75+ 354 (14.7) 175 (41.0) 4.11 (3.01–5.62)
Impact of quitting
Reference* 986 (65.0) 135 (70.6) 1.00
Duration since quitting (tertiles) <15 years 158 (10.4) 22 (11.5) 1.11 (0.69–1.79)
15–27 years 175 (11.5) 22 (11.5) 1.13 (0.73–1.75)
28+ years 199 (13.1) 12 (6.3) 0.44 (0.26–0.74)

* Non-smokers.

Adjustments: Year of birth, community size, educational attainment, nasal snuff package-years, years of exposure to hardwood dust, asbestos, organic solvents, use of nasal spray/nasal lavage and ever-use of insecticides in homes.

Greiser et al.

Greiser et al. BMC Cancer 2012 12:506   doi:10.1186/1471-2407-12-506

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