Table 5

Grade three or four treatment-related haematological adverse events by number of patients1
Adverse event Group A2(n=9) Group B3(n=6) Group C4(n=21) Group D5(n=6)
Gd 3 Gd 4 Gd 3 Gd 4 Gd 3 Gd 4 Gd 3 Gd 4
Leucopenia 2 - 3 1 4 6 3 -
Neutropenia 2 1 3 1 3 6 2 1
Thrombocytopenia - 3 - - 2 4 - 2
Anaemia 1 - - - 3 - 1 -
Any haematological toxicity 4 3 1 5 7 1 3

1Highest toxicity grade by CTCAE version 3.0 for each patient; 2 PR104 + gemcitabine.

3 PR104 + docetaxel 60; 4 PR104 + docetaxel 60 + GCSF; 5 PR104 + docetaxel 75 + GCSF.

McKeage et al.

McKeage et al. BMC Cancer 2012 12:496   doi:10.1186/1471-2407-12-496

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