Table 2

PR104 starting and maximal tolerated doses with its combination agents, their doses and administration schedules
Group PR104 dose (mg/m2) Combination Agents Schedule
Starting Maximum tolerated Agent Dose (mg/m2)
A 275 140 Gemcitabine 800 iv days 1 and 8 q 3 weekly
B 400 <200 Docetaxel 60 iv day 1 q 3 weekly
C 200 770 Docetaxel + G-CSF 60 iv day 1 q 3 weekly
D 770 ≥770 Docetaxel + G-CSF 75 iv day 1 q 3 weekly

McKeage et al.

McKeage et al. BMC Cancer 2012 12:496   doi:10.1186/1471-2407-12-496

Open Data