Table 2

DNA Repair Capacity (DRC) of women with breast cancer (BC) and women without BC by age group
Variable Women with BC n (mean DRC) Women without BC n (mean DRC) Crude OR1 Adjusted OR2 Pvalue
(95% CI) (95% CI)
  Decreasing DRC (continuous)* 285 (2.41) 539 (6.13) 2.2 (1.9, 2.4) 2.3 (2.0, 2.6) < 0.001
  DRC
  Low (< 4.3%) 246 168 13.9 (9.4, 20.4) 15.1 (10.0, 22.9) < 0.001
  High (≥ 4.3%) 39 371
  DRC levels3
  Low (0.0-3.0%) 213 66 54.6 (30.3, 98.5) 60.6 (32.1, 114.6) < 0.001
  Medium (3.01-5.8%) 57 219 4.4 (2.4, 8.0) 13.0 (8.5, 20.0) < 0.001
  High (≥5.81%) 15 254 Referent Referent

*Mean values presented in parenthesis.

Comparisons were measured with the crude1 and the adjusted2 multiple logistic regression odds ratio (OR) in the total sample divided by patients and women without breast cancer.

1Crude or unadjusted analysis: The analysis is carried out without taking into consideration potential confounders.

2Adjusted analysis: The analysis is carried out adjusting for the potential effect of all confounding variables simultaneously by using logistic regression model.

3Chi-Square for linear trend = 233.6, p< 0.001.

Matta et al.

Matta et al. BMC Cancer 2012 12:490   doi:10.1186/1471-2407-12-490

Open Data