Effect of sorafenib treatmenton cell viability ofirradiated SMMC-7721 (A) andBEL-7402 cells (B). Cells were treated with radiation, sorafenib 30 min prior to irradiation (pre-IR sorafenib), or 24 h post irradiation (post-IR sorafenib), and MTT assays were performed to measure the viability of irradiated, treated cells. Cell viability was significantly lower in the post-irradiation sorafenib group versus the irradiation or pre-irradiation sorafenib group. Mean values were compared by using ANOVA. Mean ± SD (n = 3). *P < 0.05 vs. Radiation group.
Li et al. BMC Cancer 2012 12:485 doi:10.1186/1471-2407-12-485