Table 6

Correlations between ECM1 expression and clinicopathological characteristics

Clinicopathological characteristics

N

ECM1 positive

P

ECM1 mRNA expression

P


N

rate (%)


Age (years)

< 60

30

22

73.3

1.54 ± 0.43

≥ 60

11

9

81.8

0.700

0.68 ± 0.46

0.183

Histological grade

(invasive ductal)

I+II

16

12

75.0

1.76 ± 0.71

III+IV

20

16

80.0

0.720

1.18 ± 0.39

0.483

Tumor size

T1

15

10

66.7

1.49 ± 0.60

T2

23

19

82.6

1.34 ± 0.46

T3

3

2

66.7

0.512

0.11 ± 0.08

0.275

Lymph nodal status

N0

22

16

72.7

1.48 ± 0.54

N1

12

10

83.3

1.32 ± 0.58

N2

5

3

60.0

0.81 ± 0.60

N3

2

2

100

0.121

0.54 ± 0.50

0.424

Estrogen receptor status

-

10

5

50.0

1.02 ± 0.62

+~+++

31

26

83.9

0.045*

1.40 ± 0.41

0.611

Progesterone receptor status

-

8

4

50.0

1.32 ± 0.90

+~+++

33

27

81.8

0.082

1.30 ± 0.37

0.987

HER2/neu score

- (0-1)

13

11

84.6

1.48 ± 0.69

+ (2-3)

28

20

71.4

0.458

1.23 ± 0.39

0.757


"+", "++" and "+++" for ECM1 immunochemistry staining was all grouped together as "+"

* P < 0.05 is considered statistically significant

Wu et al. BMC Cancer 2012 12:47   doi:10.1186/1471-2407-12-47

Open Data