Representative IHC staining of VEGF-C (200×). A-D: VEGF-C staining was mainly located in the cytoplasm of breast cancer cells: A. VEGF-C negative; B. + VEGF-C staining; C. ++ VEGF-C staining; D. +++ VEGF-C staining. E-F normal breast epithelium: E. VEGF-C negative; F. breast ductal epithelial cells classified ++ for cytoplasmic VEGF-C staining. G-H lymph node metastases: G. metastatic cells were negative for VEGF-C staining; H. cytoplasm of metastatic cells classified + for VEGF-C staining.
Wu et al. BMC Cancer 2012 12:47 doi:10.1186/1471-2407-12-47