Open Access Research article

Inflammatory gene variants and the risk of biliary tract cancers and stones: a population-based study in China

Felipe A Castro1*, Jill Koshiol1, Ann W Hsing1, Yu-Tang Gao2, Asif Rashid3, Lisa W Chu1, Ming-Chang Shen4, Bing-Shen Wang5, Tian-Qua Han6, Bai-He Zhang7, Shelley Niwa8, Kai Yu1, Hong Zhang9, Stephen Chanock110 and Gabriella Andreotti1

Author Affiliations

1 Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd., EPS 7063, Rockville, MD, 20892, USA

2 Shanghai Cancer Institute, Shanghai, China

3 Department of Pathology, MD Anderson Cancer Center, Houston, TX, USA

4 Shanghai Tumor Hospital, Shanghai, China

5 Zhongshan Hospital, Fudan University, Shanghai, China

6 Department of Surgery, Ruijin Hospital, Shanghai Second Medical University, Shanghai, China

7 Institute of Oriental Hepatobiliary Surgery, Second Military Medical University, Shanghai, China

8 Westat, Rockville, MD, USA

9 Institute of Biostatistics, School of Life Science, Fudan University, Shanghai, China

10 Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Advanced Technology Center, Bethesda, Maryland, 20892-4605, USA

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BMC Cancer 2012, 12:468  doi:10.1186/1471-2407-12-468

Published: 11 October 2012

Additional files

Additional file 1:

Table S1. Selected characteristics of biliary tract cancer cases, stone cases, and controls in the Shanghai population.

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Additional file 2:

Table S2. Associationsa between SNPs and biliary stones and biliary tract cancers based on the additive model in the Shanghai population.

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Additional file 3:

Table S3. Selected inflammatory genes and their association with biliary stones and cancer in the Shanghai population.

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