Effects of SPARC knockdown on cell migration and invasion. (A) The images of cells migrating PVPF filters as examined by cell migration assay using Boyden chambers. (B) The images of cells invading Matrigel-coated membranes as examined by cell invasion assay using Boyden chambers. (Magnification ×200). (C) The average invading or migrating cell counts of SPARC shRNA infected cells, control shRNA infected cells and non-infected cells. *P<0.05 versus control.
Chen et al. BMC Cancer 2012 12:464 doi:10.1186/1471-2407-12-464