Expression of EGFR, pAKT and hypoxia in vivo. Expression of EGFR and pAKT in relation to hypoxia was analyzed by immunohistochemical analysis in UT-SCC xenograft tumors of 4 different lines. Left column: EGFR (red), pAKT (green), vessels (blue). Right column: EGFR (red), hypoxia (green), vessels (blue). Non-specific staining present in necrotic regions. Scale bars represent 500 μm. Magnification: 100X.
Stegeman et al. BMC Cancer 2012 12:463 doi:10.1186/1471-2407-12-463