Table 1

Patient charcateristics and clinicopathological parameters in relation to aquaporin 3 protein expression status
Parameter Total (%) AQP3 positive (%) AQP3 negative (%) p value
Number of patients 87 (100.0) 51 (58.6) 36 (41.4)
Gender
Female 15 (17.2) 7 (46.7) 8 (53.3) p=0.227
Male 72 (82.8) 44 (61.1) 28 (38.9)
Age
median age (years) 70 ±11.5 68 ±12.6 73 ±9.3 p=0.095
age range (years) 41-98 41-98 50-88
History
first diagnosis of UBC 75 (82.8) 43 (57.3) 32 (42.7) p=0.390
recurrent tumour 12 (17.2) 8 (66.7) 4 (33.3)
WHO grading 1973
pT1G2 15 (17.2) 8 (53.3) 7 (46.7) p=0.429
pT1G3 72 (82.7) 43 (59.7) 29 (40.3)
Cofactors
associated CIS 36 (41.4) 20 (55.6) 16 (44.4) p=0.394
multifocal tumours 17 (19.5) 11 (64.7) 6 (35.3) p=0.388
tumour size ≥3cm 41 (47.1) 27 (65.9) 14 (34.1) p=0.141
BCG instillations
≤ 6 instillations 68 (78.2) 42 (61.8) 26 (38.2) p=0.194
> 6 instillations 19 (21.8) 9 (47.4) 10 (52.6)

AQP3 aquaporin 3 protein; BCG Bacillus Calmette-Guérin; CIS carcinoma in situ; UBC urothelial bladder carcinoma; WHO world health organisation.

Otto et al.

Otto et al. BMC Cancer 2012 12:459   doi:10.1186/1471-2407-12-459

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