Table 1 |
||||
| Patient charcateristics and clinicopathological parameters in relation to aquaporin 3 protein expression status | ||||
| Parameter | Total (%) | AQP3 positive (%) | AQP3 negative (%) | p value |
| Number of patients | 87 (100.0) | 51 (58.6) | 36 (41.4) | |
| Gender | ||||
| Female | 15 (17.2) | 7 (46.7) | 8 (53.3) | p=0.227 |
| Male | 72 (82.8) | 44 (61.1) | 28 (38.9) | |
| Age | ||||
| median age (years) | 70 ±11.5 | 68 ±12.6 | 73 ±9.3 | p=0.095 |
| age range (years) | 41-98 | 41-98 | 50-88 | |
| History | ||||
| first diagnosis of UBC | 75 (82.8) | 43 (57.3) | 32 (42.7) | p=0.390 |
| recurrent tumour | 12 (17.2) | 8 (66.7) | 4 (33.3) | |
| WHO grading 1973 | ||||
| pT1G2 | 15 (17.2) | 8 (53.3) | 7 (46.7) | p=0.429 |
| pT1G3 | 72 (82.7) | 43 (59.7) | 29 (40.3) | |
| Cofactors | ||||
| associated CIS | 36 (41.4) | 20 (55.6) | 16 (44.4) | p=0.394 |
| multifocal tumours | 17 (19.5) | 11 (64.7) | 6 (35.3) | p=0.388 |
| tumour size ≥3cm | 41 (47.1) | 27 (65.9) | 14 (34.1) | p=0.141 |
| BCG instillations | ||||
| ≤ 6 instillations | 68 (78.2) | 42 (61.8) | 26 (38.2) | p=0.194 |
| > 6 instillations | 19 (21.8) | 9 (47.4) | 10 (52.6) | |
AQP3 aquaporin 3 protein; BCG Bacillus Calmette-Guérin; CIS carcinoma in situ; UBC urothelial bladder carcinoma; WHO world health organisation.
Otto et al. BMC Cancer 2012 12:459 doi:10.1186/1471-2407-12-459
