Kaplan-Meier analysis of recurrence-free (RFS) (a), progression-free (PFS) (b) and cancer-specific survival (CSS) (c) in relation to aguaporin 3 expression in stage T1 urothelial bladder carcinoma. While the lower RFS of AQP3 negative patients did not reach statistical significance, loss of AQP3 was associated with a statistically significantly worse PFS. There was no statistically significant difference in outcome regarding CSS.
Otto et al. BMC Cancer 2012 12:459 doi:10.1186/1471-2407-12-459