Akt Phosphorylation. Glioblastoma cells were stimulated with PMA prior to parthenolide treatment, and Akt phosphorylation was analysed by western blotting. Representative blots are shown. Akt expression and phosphorylation in both glioblastoma cell lines was stimulated by PMA, but suppressed by parthenolide in a dose-dependent manner.
Nakabayashi and Shimizu BMC Cancer 2012 12:453 doi:10.1186/1471-2407-12-453