In vitro angiogenesis assay. Glioblastoma cells were treated with parthenolide, and in vitro angiogenesis was assessed using a modified tube formation assay. (A) Representative tube formation data. (B) Tube formation was significantly suppressed by parthenolide in a dose-dependent manner. Data is presented as mean ± SD (n = 3). Points indicate bars + SD; * indicates p < 0.0001. Bar = 5 mm.
Nakabayashi and Shimizu BMC Cancer 2012 12:453 doi:10.1186/1471-2407-12-453