Table 2

Grade ≥ 3 adverse events
Toxicity Grade 3 Grade 4 Grade 5 Total
Hematologic 7 (21%)
 Anemia 1 (3%) 0 0 1 (3%)
 Neutropenia 4 (12%) 1 (3%) 0 5 (15%)
 Febrile Neutropenia 0 1 (3%) 0 1 (3%)
 Thrombocytopenia 0 0 0 0
Nonhematologic
 Cardiac 4 (12%)
  Systolic dysfunction 2 (6%) 0 0 2 (6%)
  Cardiac arrest 0 0 1 (3%) 1 (3%)
  Myocardial infarction 0 1 (3%) 1 (3%) 2 (6%)
 Edema 1 (3%) 0 0 1 (3%)
 Fatigue 10 (29%) 1 (3%) 0 11 (32%)
 Infection 3 (9%) 0 1 (3%) 4 (12%)
 Gastrointestinal 4 (12%)
  Constipation 2 (6%) 0 0 2 (6%)
  Diarrhea 2 (6%) 0 0 2 (6%)
 Pulmonary 3 (9%)
  Embolism 1 (3%) 0 0 1 (3%)
  Pneumonitis 0 0 1 (3%) 1 (3%)
  Pneumothorax 0 1 (3%) 0 1 (3%)
 Bladder/Kidney stone 2 (6%) 0 0 2 (6%)

Bauman et al.

Bauman et al. BMC Cancer 2012 12:449   doi:10.1186/1471-2407-12-449

Open Data