Macroscopic view of large bowel. Macroscopic view of large bowel of KAD rats that were not given 5-FU (A) and that were given 50 mg/kg 5-FU (B). Colon tumors that developed in both groups were mainly distributed in the rectum and distal colon, which was assumed to be within 8 cm from the anus. No tumors were observed in the proximal colon. Left side: anus. Right side: cecum. Bar: 2 cm.
Yoshimi et al. BMC Cancer 2012 12:448 doi:10.1186/1471-2407-12-448