Table 3

Associations of measures of timing of sunlight exposure in BCC and SCC cases and controls
Controls (n = 316) Basal cell carcinoma (n = 218) Squamous cell carcinoma (n = 169)
Variable n (%) n (%) OR (95% CI)1 OR (95% CI)2 n (%) OR (95% CI)1 OR (95% CI)2
# of moles on forearms
None 220 (71.4) 155 (71.8) 1.00 (reference) 1.00 (reference) 115 (69.7) 1.00 (reference) 1.00 (reference)
<10 80 (26.0) 53 (24.5) 0.84 (0.54-1.31) 0.65 (0.40-1.06) 39 (23.6) 0.92 (0.56-1.52) 0.94 (0.54-1.64)
≥10 8 (2.6) 8 (3.7) 1.65 (0.57-4.77) 1.75 (0.55-5.61) 11 (6.7) 3.27 (1.12-9.58) 2.69 (0.75-9.59)
ptrend = 0.96 ptrend = 0.45 ptrend = 0.25 ptrend = 0.43
# of moles on entire body
None 118 (39.1) 79 (36.9) 1.00 (reference) 1.00 (reference) 56 (34.1) 1.00 (reference) 1.00 (reference)
<10 147 (48.7) 107 (50.0) 1.11 (0.73-1.67) 1.03 (0.66-1.60) 76 (46.3) 1.15 (0.72-1.86) 1.22 (0.71-2.09)
≥10 37 (12.3) 28 (13.1) 1.18 (0.64-2.19) 1.06 (0.55-2.04) 32 (19.5) 2.12 (1.11-4.06) 2.16 (1.03-4.52)
ptrend = 0.54 ptrend = 0.86 ptrend = 0.04 ptrend = 0.06
Age at 1st blistering sunburn
None 101 (32.9) 54 (25.2) 1.00 (reference) 1.00 (reference) 38 (23.5) 1.00 (reference) 1.00 (reference)
<10 years 62 (20.2) 47 (22.0) 1.97 (1.14-3.42) 1.35 (0.73-2.49) 46 (28.4) 2.25 (1.22-4.13) 1.07 (0.53-2.15)
10–20 years 108 (35.2) 84 (39.3) 2.15 (1.32-3.52) 1.73 (1.00-2.99) 65 (40.1) 2.37 (1.34-4.21) 1.62 (0.86-3.04)
>20 years 36 (11.7) 29 (13.6) 1.71 (0.89-3.28) 1.67 (0.83-3.37) 13 (8.0) 0.96 (0.42-2.20) 0.81 (0.33-2.01)
ptrend = 0.01 ptrend = 0.05 ptrend = 0.17 ptrend = 0.53
Age at 1st tanning bed use
Never used 209 (67.0) 175 (80.3) 1.00 (reference) 1.00 (reference) 127 (76.5) 1.00 (reference) 1.00 (reference)
≤20 years 38 (12.2) 20 (9.2) 1.09 (0.58-2.06) 1.10 (0.55-2.18) 23 (13.9) 1.97 (1.01-3.85) 1.97 (0.91-4.27)
>20 years 65 (20.8) 23 (10.6) 0.64 (0.64-1.12) 0.56 (0.30-1.05) 16 (9.6) 0.77 (0.40-1.50) 0.78 (0.37-1.65)
ptrend = 0.46 ptrend = 0.33 ptrend = 0.96 ptrend = 0.98
Daily sunlight exposure by age at exposure
Teens
Low 63 (20.9) 27 (13.6) 1.00 (reference) 1.00 (reference) 21 (13.2) 1.00 (reference) 1.00 (reference)
Medium 104 (34.4) 68 (34.2) 1.28 (0.71-2.30) 1.18 (0.62-2.25) 55 (34.6) 1.24 (0.64-2.42) 0.94 (0.45-1.97)
High 135 (44.7) 104 (52.3) 1.38 (0.78-2.43) 1.47 (0.78-2.77) 83 (52.2) 1.43 (0.75-2.73) 1.40 (0.68-2.89)
Twenties
Low 121 (40.2) 62 (31.0) 1.00 (reference) 1.00 (reference) 53 (33.3) 1.00 (reference) 1.00 (reference)
Medium 114 (37.9) 79 (39.5) 1.20 (0.77-1.88) 1.35 (0.82-2.21) 51 (32.1) 0.82 (0.49-1.37) 0.97 (0.54-1.73)
High 66 (21.9) 59 (29.5) 1.22 (0.73-2.31) 1.31 (0.75-2.31) 55 (34.6) 1.40 (0.80-2.44) 1.56 (0.83-2.91)
Thirties
Low 152 (51.9) 87 (43.9) 1.00 (reference) 1.00 (reference) 64 (40.3) 1.00 (reference) 1.00 (reference)
Medium 103 (35.2) 63 (31.8) 0.90 (0.58-1.39) 0.98 (0.60-1.58) 62 (39.0) 1.08 (0.66-1.75) 1.36 (0.78-2.37)
High 38 (13.0) 48 (24.2) 1.20 (0.68-2.10) 1.28 (0.69-2.36) 33 (20.8) 1.15 (0.61-2.18) 1.30 (0.63-2.68)
Past 10 years
Low 126 (57.3) 76 (44.2) 1.00 (reference) 1.00 (reference) 80 (54.1) 1.00 (reference) 1.00 (reference)
Medium 65 (29.5) 59 (34.3) 1.05 (0.64-1.74) 1.15 (0.66-2.01) 40 (27.0) 0.77 (0.45-1.31) 1.13 (0.61-2.10)
High 29 (13.2) 37 (21.5) 1.41 (0.74-2.68) 1.62 (0.79-3.30) 28 (18.9) 1.16 (0.59-2.25) 1.57 (0.73-3.36)

1Odds ratios (OR) and 95% confidence intervals (CI) adjusted for age, gender, education, and history of ever smoking.

2OR and 95% CI adjusted for age, gender, education, history of ever smoking, cutaneous sensitivity and tanning ability to sunlight exposure.

Iannacone et al.

Iannacone et al. BMC Cancer 2012 12:417   doi:10.1186/1471-2407-12-417

Open Data