Table 7

Cox proportional hazard models (59 patients without lymph node metastasis)
Variable Crude HR 95% CI P value AHR 95% CI P value
PIK3CA amplification 2.83 1.08-7.36 0.003 3.13 1.16-8.4 0.024
Mutation (PIK3CA K-Ras) 0.73 0.09-5.6 0.77 0.83 0.1-6.78 0.86
Age 0.97 0.93-1.00 0.13 0.95 0.91-1.0 0.075
Gender 1.22 0.52-2.84 0.64 1.06 0.42-2.65 0.89
Smoking status 1.01 0.99-1.03 0.08 1.02 0.99-1.04 0.06

Adjusted for age, gender, smoking status, mutation status.

HR, hazard ratio; CI, confidence interval; AHR, adjusted hazard ratio.

Cox proportional hazard models were computed to determine the significance of PIK3CA amplification with adjustment for age, gender, smoking status and mutation status.

Suda et al.

Suda et al. BMC Cancer 2012 12:416   doi:10.1186/1471-2407-12-416

Open Data