Table 3 |
|||
| Crude and adjusted odds ratios (OR) and 95% confidence intervals (CI) of the 493 cases and 493 controls in the study in Southern Iran | |||
| Parameter | Events | Crude OR (95% CI) | Adjusted OR (95%CI)1 |
| Cases/Controls | |||
| Parity | |||
| Nulliparous | 38/12 | 1 | 1 |
| 1 – 3 | 130/76 | 0.50 (0.25 – 1.02) | 0.53 (0.25 – 1.15) |
| 4 – 6 | 227/197 | 0.34 (0.17 – 0.67) | 0.47 (0.29 – 0.93) |
| 7+ | 98/208 | 0.14 (0.07 – 0.28) | 0.23 (0.11 – 0.50) |
| P for trend | < 0.001 | < 0.001 | |
| Age at menarche (years) | |||
| < 12 | 42/25 | 1.80(1.07 – 3.02) | 1.72 (0.96 – 3.07) |
| 12 – 15 | 395/425 | 1 | 1 |
| > 15 | 56/43 | 1.40 (0.91 – 2.13) | 1.11 (0.86 – 2.24) |
| P for trend | 0.75 | 0.09 | |
| Education | |||
| None | 179/292 | 1 | 1 |
| Elementary | 155/123 | 2.05 (1.51 – 2.79) | 1.33 (0.83 – 2.29) |
| High school | 108/62 | 2.84 (1.95 – 4.12) | 1.26 (0.78 – 2.03) |
| University | 51/16 | 5.19 (2.81 – 9.59) | 1.50 (0.64 – 3.48) |
| P for trend | < 0.001 | 0.06 | |
| Occupation | |||
| Housewife | 391/462 | 1 | 1 |
| Employed | 102/31 | 3.88 (2.51 – 5.99) | 2.05 (1.15 – 3.92) |
| Height (cm)2 | |||
| ≤ 151 | 143/132 | 1 | 1 |
| 152 – 156 | 160/122 | 1.21(0.86 – 1.69) | 1.12 (0.77 – 1.62) |
| 157 – 160 | 90/163 | 0.50(0.35 – 0.72) | 0.73 (0.49 – 1.71) |
| > 160 | 85/76 | 1.03(0.69 – 1.52) | 1.08 (0.69 – 1.66) |
| Missing | 15/0 | ||
| P for trend | 0.06 | 0.10 | |
| BMI (Overall) | |||
| < 18.5 | 4/14 | 0.38 (0.12 – 1.19) | 0.60 (0.17 – 2.11) |
| 18.5 – 24.9 | 129/181 | 1 | 1 |
| 25 – 29.9 | 208/193 | 1.43 (1.06 – 1.95) | 1.39 (1.02 – 1.94) |
| ≥ 30 | 141/119 | 1.58 (1.12 – 2.22) | 1.61 (1.18 – 2.30) |
| Missing | 15/0 | ||
| P for trend | <0.001 | 0.01 | |
| BMI (age <58 years) | |||
| < 18.5 | 4/5 | 0.90 (0.23 – 3.55) | - |
| 18.5 – 24.9 | 78/90 | 1 | 1 |
| 25 – 29.9 | 126/123 | 1.18 (0.79 – 1.74) | 1.27 (0.80 – 2.02) |
| ≥ 30 | 89/82 | 1.25(0.81 – 1.91) | 1.21 (0.73 – 1.99) |
| P for trend | 0.30 | 0.47 | |
| BMI (age ≥58 years) | |||
| < 18.5 | 0/9 | - | - |
| 18.5 – 24.9 | 47/77 | 1 | 1 |
| 25 – 29.9 | 82/70 | 1.91 (1.18 – 3.11) | 1.56 (0.97 – 2.65) |
| ≥ 30 | 52/37 | 2.30 (1.32 – 4.01) | 2.34 (1.33 – 4.14) |
| P for trend | 0.002 | 0.008 | |
| P for interaction3 | 0.16 | 0.09 | |
| F.H. of breast cancer | |||
| No | 422/470 | 1 | 1 |
| Yes | 71/23 | 3.50 (2.37 – 5.17) | 2.61 (1.72 – 3.96) |
| 1st relative | 43/15 | 3.19(1.73 – 5.86) | 2.13 (1.20 – 4.46) |
| 2nd relative | 28/8 | 3.89(1.74 – 8.69) | 1.98 (0.96 – 5.62) |
| P for trend | < 0.001 | 0.003 | |
(Abbreviation F.H.: Family History).
1Adjusted for all variables in the table in addition to age.
2Height was categorized based on approximate quartile values of the control population.
3Multiplicative interaction between BMI and age.
Ghiasvand et al. BMC Cancer 2012 12:414 doi:10.1186/1471-2407-12-414
