Simvastatin modulates expression of genes in PC3 cells involved in the extrinsic pathway regulating apoptosis. Bar graph showing changes in the mRNA levels of genes such as Bcl-2, Fas-L, Lhx4, Nme5, Traf1 and Trp53inp1with 24h simvastatin treatment normalized to multiple housekeeping genes. The data are presented as mean ± SD (n=4 of quadruplicate experiments).
Goc et al. BMC Cancer 2012 12:409 doi:10.1186/1471-2407-12-409