Figure 3.

Western blot showing loss of SDHA expression in the young adult GIST carrying a germline SDHA exon 2 mutation p.Arg31X (GIST318, primary gastric tumor; GIST353, liver metastasis), as well as in the young adult GIST carrying a somatic SDHA exon 2 mutation (GIST118, peritoneal metastasis). Remaining WT GIST (GIST#289, 491, 507, 517) lacking SDHA mutations showed preserved SDHA protein expression.

Italiano et al. BMC Cancer 2012 12:408   doi:10.1186/1471-2407-12-408
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