Table 2

*Adjusted ORs and 95% CI for the relationship between the C-peptide, IGFBP-1 and adenoma status, overall, and among men and women
Overall Men Women
Measure Case/control (n) Adjusted OR1(95% CI) Case/control (n) Adjusted OR1(95% CI) Case/control (n) Adjusted OR1(95% CI)
C-Peptide
Quartile 1 29/106 1.0 (Referent) 14/40 1.0 (Referent) 15/66 1.0 (Referent)
Quartile 2 32/108 1.2 (0.6, 2.1) 19/42 1.9 (0.7, 4.8) 13/66 0.8 (0.3, 2.1)
Quartile 3 40/101 1.4 (0.8, 2.6) 24/40 2.6 (1.0, 6.9) 16/61 1.0 (0.4, 2.4)
Quartile 4 71/105 2.2 (1.2, 4.0) 48/45 4.4 (1.7, 10.9) 23/60 1.6 (0.7, 4.0)
P trend 0.04 0.006 0.58
IGFBP-1
Quartile 1 51/106 1.0 (Referent) 36/41 1.0 (Referent) 15/65 1.0 (Referent)
Quartile 2 52/103 0.9 (0.5, 1.6) 35/49 0.7 (0.3, 1.5) 17/54 1.2 (0.5, 3.0)
Quartile 3 37/105 0.7 (0.4, 1.2) 22/42 0.5 (0.2, 1.0) 15/63 1.3 (0.5, 3.1)
Quartile 4 29/105 0.6 (0.3, 1.1) 10/35 0.3 (0.1, 0.7) 19/70 1.4 (0.6, 3.4)
P trend 0.13 0.007 0.47
Insulin
Quartile 1 21/88 1.0 (Referent) 14/37 1.0 (Referent) 7/51 1.0 (Referent)
Quartile 2 27/84 1.7 (0.8, 3.7) 17/32 1.3 (0.5, 3.5) 10/52 2.6 (0.7, 9.0)
Quartile 3 40/81 2.6 (1.2, 5.5) 29/31 3.1 (1.2, 7.9) 11/50 2.4 (0.7, 8.6)
Quartile 4 55/84 3.5 (1.7, 7.4) 31/33 2.8 (1.1, 7.1) 24/51 4.6 (1.5, 15.3)
P trend 0.002 0.02 0.03

*Adjusted for race, sex, BMI, WHR, diabetes history, alcohol intake, smoking and red meat intake.

Vidal et al.

Vidal et al. BMC Cancer 2012 12:389   doi:10.1186/1471-2407-12-389

Open Data