Table 2

Correlation of Gene expression and segment copy number
Gene expression Number of genes Number of segments with
Amplification Deletion No variation Total
up 330 8 0 305 313
down 170 2 0 213 215
10 0 518 528

The correlation between the top 500 differentially expressed genes and the segment copy numbers found within the coding regions was examined. For each up- or down-regulated gene the number of segments with an increase (amplification), a decrease (deletion) or no variation in copy number values were counted. Interestingly, a decrease in segmental copy number was neither found for up-regulated nor for down-regulated genes. Only 8 of 313 segments associated to 330 up-regulated genes show an increase in segmental copy number, whereas the remaining 98.48% of the segments show no significant change.

StandfuƟ et al.

StandfuƟ et al. BMC Cancer 2012 12:380   doi:10.1186/1471-2407-12-380

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