|Correlation of Gene expression and segment copy number|
|Gene expression||Number of genes||Number of segments with|
The correlation between the top 500 differentially expressed genes and the segment copy numbers found within the coding regions was examined. For each up- or down-regulated gene the number of segments with an increase (amplification), a decrease (deletion) or no variation in copy number values were counted. Interestingly, a decrease in segmental copy number was neither found for up-regulated nor for down-regulated genes. Only 8 of 313 segments associated to 330 up-regulated genes show an increase in segmental copy number, whereas the remaining 98.48% of the segments show no significant change.
Standfuß et al.
Standfuß et al. BMC Cancer 2012 12:380 doi:10.1186/1471-2407-12-380