|Correlation of Gene expression and SNP copy number|
|Gene expression||Number of genes||Number of SNPs with|
The correlation between the top 500 differentially expressed genes and the copy number of SNPs found within the coding regions was examined. For each up- or down-regulated gene the number of SNPs with an increase (amplification), a decrease (deletion) or no variation in copy number were counted. All in all, 5,350 SNPs were found within differentially expressed 500 genes; 7.5% of them had significant variations in SNP copy numbers (underlined). For merely 358 SNPs within the 330 up-regulated genes, an increased copy number was detected. For the 170 down-regulated genes only 41 SNPs were found to have a decrease in copy number.
Standfuß et al.
Standfuß et al. BMC Cancer 2012 12:380 doi:10.1186/1471-2407-12-380